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Chronic lung disease secondary to ammonia inhalation injury: A report on three cases
Author(s) -
de la Hoz Rafael E.,
Schlueter Donald P.,
Rom William N.
Publication year - 1996
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/(sici)1097-0274(199602)29:2<209::aid-ajim12>3.0.co;2-7
Subject(s) - medicine , inhalation , lung , lung disease , respiratory disease , occupational lung disease , obstructive lung disease , intensive care medicine , disease , pulmonary disease , pathology , anesthesia
Inhalation of highly hydrosoluble toxicants, like ammonia, can be associated with chronic lung diseases, which have been partially characterized. We present the cases of three patients who were evaluated 2 years after massive exposure to ammonia in occupational settings. They presented with chronic dyspnea, and clinical pictures consistent with restrictive lung dysfunction, obstructive lung disease, and bronchial hyper‐reactivity and small airways disease, respectively. The findings in 94 reported cases of inhalation injury due to massive exposure to ammonia are reviewed; in 35 cases follow‐up for at least 1 year was available. The range of chronic pulmonary diseases associated with ammonia inhalation injury is reviewed, and suggestions for appropriate diagnostic evaluation are made. © 1996 Wiley‐Liss, Inc.