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Issues for statisticians in pharmaco‐economic evaluations
Author(s) -
Grieve A. P.
Publication year - 1998
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/(sici)1097-0258(19980815/30)17:15/16<1715::aid-sim973>3.0.co;2-6
Subject(s) - computer science , bayesian probability , range (aeronautics) , confidence interval , management science , econometrics , operations research , data science , economics , statistics , artificial intelligence , mathematics , materials science , composite material
Economic evaluations of new pharmaceutical products are of increasing importance to pharmaceutical companies. In this paper we investigate a number of topics of greater or lesser importance to statisticians who need to involve themselves in pharmaco‐economic evaluations. These range from the need to consider whether traditional randomized clinical trials provide the most appropriate setting for an economic evaluation, to the more technical question of how to handle cost‐effectiveness ratio data, including the issue of the most appropriate inferential apparatus – hypothesis testing, confidence intervals or Bayesian methods. © 1998 John Wiley & Sons, Ltd.