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Modelling cure rates using the Gompertz model with covariate information
Author(s) -
Gieser Peter W.,
Chang Myron N.,
Rao P. V.,
Shuster Jonathan J.,
Pullen Jeanette
Publication year - 1998
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/(sici)1097-0258(19980430)17:8<831::aid-sim790>3.0.co;2-g
Subject(s) - covariate , gompertz function , statistics , estimation , cure rate , econometrics , proportional hazards model , function (biology) , computer science , mathematics , medicine , surgery , biology , management , economics , evolutionary biology
We extend the modified Gompertz hazard function, first used by Cantor and Shuster for estimation of cure rates from pediatric clinical trials, by including covariate effects. The extended model provides a convenient method for estimation of the cure rate as a function of treatments and covariates. © 1998 John Wiley & Sons, Ltd.