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Accurate mass determination by multiple sprayers nano‐electrospray mass spectrometry on a magnetic sector instrument
Author(s) -
Takahashi Yutaka,
Fujimaki Susumu,
Kobayashi Tatsuji,
Morita Tetsuichiro,
Higuchi Tetsuo
Publication year - 2000
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(20000615)14:11<947::aid-rcm970>3.0.co;2-n
Subject(s) - chemistry , sprayer , mass spectrometry , analytical chemistry (journal) , electrospray ionization , nano , electrospray , extractive electrospray ionization , body orifice , chromatography , sample (material) , sample preparation in mass spectrometry , chemical engineering , ecology , geotechnical engineering , engineering , biology
A new technique for accurate mass determination by using multiple sprayers nano‐electrospray ionization mass spectrometry (nano‐ESI‐MS) on a magnetic sector instrument is described. Metal coated glass capillaries were used as nano‐ESI sprayers. One of the sprayers was used for the reference compound solution, and others were used for the introduction of sample solutions. The spectra of the different compounds were obtained by shifting each sprayer's position relative to the sampling orifice. The accurate masses of several standard compounds were obtained with good accuracy, without problems arising from differences in ionization efficiency between the sample compounds and reference compound. Copyright © 2000 John Wiley & Sons, Ltd.