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252 Cf Plasma desorption mass spectrometric study of interactions of steroid glycosides with amino acids
Author(s) -
Pilipenko V. V.,
Sukhodub L. F.,
Aksyonov S. A.,
Kalinkevich A. N.,
Kintia P. K.
Publication year - 2000
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(20000530)14:10<819::aid-rcm949>3.0.co;2-i
Subject(s) - chemistry , aglycone , amino acid , glycoside , steroid , side chain , mass spectrometry , desorption , chromatography , stereochemistry , organic chemistry , biochemistry , polymer , adsorption , hormone
252 Cf Plasma desorption with time‐of‐flight mass spectrometry (TOF‐PDMS) has been applied to comparative studies of the interactions of steroid glycosides (SGs) of the spirostan series with amino acids. SGs can interact with amino acids to form heteroclusters of the type [SG + aminoacid + H] + and [SG + aminoacid + K] + . It is shown how the affinity of SGs for amino acids depends on the structures of both the SG carbohydrate chain and the SG aglycone, and on the nature of the amino acid side chain. Copyright © 2000 John Wiley & Sons, Ltd.