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Detection of oxidative species for 4‐phenoxyphenol derivatives during the electrospray ionization process
Author(s) -
Wu Yunhui,
Wang Hong
Publication year - 2000
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(20000515)14:9<756::aid-rcm940>3.0.co;2-g
Subject(s) - chemistry , mass spectrometry , ion , electrospray ionization , tandem mass spectrometry , ion source , aqueous solution , chromatography , solvent , electrospray , nitrogen , analytical chemistry (journal) , organic chemistry
Analyses by flow injection as well as liquid chromatography/mass spectrometry (LC/MS) and liquid chromatography/tandem mass spectrometry (LC/MS/MS) were performed with four 4‐phenoxyphenol derivatives. When ambient temperature nitrogen gas was used to facilitate solvent evaporation, [M + H] + , [M + NH 4 ] + , and [2M + NH 4 ] + ions were observed as the major ions. As the nitrogen gas temperature increased from ambient to 250 and 450 °C, [M] +. , [M − 1] + and [M + 15] + ions were the predominant ions. Heat‐induced oxidation was found to be the primary source for the formation of oxidative species. Aqueous solvents were found to be essential for the formation of the [M + 15] + ions. The [M] +. and [M + 15] + ions were further characterized by tandem mass spectrometry. Based on the MS/MS data, it was proposed that the [M + 15] + ions were the in‐source generated 1,2‐quinone ions. Copyright © 2000 John Wiley & Sons, Ltd.