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Mass spectral fragmentation patterns of new 5‐acetyl‐4‐aryl‐6‐methyl‐2( 1H )pyridones
Author(s) -
Martinez Roberto,
Suarez Margarita,
Martin Nazario,
Ochoa Estael,
Seoane Carlos,
Verdecia Yamila
Publication year - 1999
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(19991115)13:21<2180::aid-rcm772>3.0.co;2-s
Subject(s) - chemistry , ketene , fragmentation (computing) , mass spectrum , aryl , electron ionization , hydrogen atom , medicinal chemistry , cleavage (geology) , bond cleavage , ion , nitrogen , nitrogen atom , spectral line , photochemistry , stereochemistry , organic chemistry , group (periodic table) , catalysis , ionization , alkyl , physics , geotechnical engineering , astronomy , fracture (geology) , computer science , engineering , operating system
The electron impact mass spectra of new 5‐acetyl‐4‐aryl‐6‐methyl‐2( 1H )pyridones have been studied. A dominant peak in all the spectra is due to cleavage of the CO–NH bond of the amido group with charge retention on the carbonyl group. This fragmentation is followed by a hydrogen rearrangement to the nitrogen atom forming ketene intermediates; this pathway leads to a highly stabilized ion which constitutes the base peak in the spectra in most of the compounds studied. Copyright © 1999 John Wiley & Sons, Ltd.