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Characterization of 3‐methoxyflavones using fast‐atom bombardment and collision‐induced dissociation tandem mass spectrometry
Author(s) -
Ma Y. L.,
Heuvel H. Van den,
Claeys M.
Publication year - 1999
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(19991015)13:19<1932::aid-rcm735>3.0.co;2-w
Subject(s) - chemistry , fragmentation (computing) , collision induced dissociation , fast atom bombardment , tandem mass spectrometry , protonation , ion , dissociation (chemistry) , mass spectrometry , tandem , analytical chemistry (journal) , chromatography , organic chemistry , materials science , computer science , composite material , operating system
A mass spectrometric method based on the combined use of fast‐atom bombardment (FAB), collision‐induced dissociation (CID) and linked scanning at constant B/E has been used for the analysis of the fragmentation behavior of protonated 3‐methoxyflavones (3‐MFs). It is shown that several diagnostic ions such as 1,3 A + and 0,2 B + ions allow for an unambiguous localization of functions in the A‐ and B‐rings and that the position of an additional methoxy group in the B‐ring could be determined by a detailed analysis of the spectral patterns. Isomeric 3‐MFs can be differentiated using this methodology. General fragmentation patterns of 3‐MFs are discussed and plausible formation mechanisms of relatively abundant fragment ions are proposed. Copyright © 1999 John Wiley & Sons, Ltd.