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High throughput liquid chromatography/mass spectrometric analyses using a novel multiplexed electrospray interface
Author(s) -
de Biasi Verner,
Haskins Neville,
Organ Andrew,
Bateman Robert,
Giles Kevin,
Jarvis Stuart
Publication year - 1999
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(19990630)13:12<1165::aid-rcm638>3.0.co;2-4
Subject(s) - chemistry , chromatography , electrospray , mass spectrometry , multiplexing , electrospray mass spectrometry , electrospray ionization , analytical chemistry (journal) , interface (matter) , molecule , organic chemistry , gibbs isotherm , electrical engineering , engineering
A novel four‐ channel multiplexed electrospray liquid chromatography interface is described. This device has been used to analyse both single components and mixtures by liquid chromatography/mass spectrometry (LC/MS) as well as synthetic samples prepared by automated procedures. These data provided unambiguous molecular weight assignments to both major components and synthetic by‐products in these samples. In this work particular attention has also been paid to the elimination of interchannel crosstalk. Copyright © 1999 John Wiley & Sons, Ltd.