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Detection of dicarboxylic acids in aqueous samples using membrane inlet mass spectrometry with desorption chemical ionization
Author(s) -
Ketola Raimo A.,
Lauritsen Frants R.
Publication year - 1999
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(19990430)13:8<749::aid-rcm553>3.0.co;2-b
Subject(s) - chemistry , chemical ionization , dicarboxylic acid , aqueous solution , mass spectrometry , chromatography , detection limit , analytical chemistry (journal) , desorption , ionization , ion , organic chemistry , adsorption
In order to detect highly polar organic compounds in water using membrane inlet mass spectrometry (MIMS), we designed a desorption chemical ionization ion source with a tubular polyacrylonitrile membrane positioned in the center of the chemical ionization (Cl) ion plasma. With this system we have for the first time been able to detect dicarboxylic acids (malonic and succinic acid) in aqueous samples with a MIMS system. The dicarboxylic acids were detected with both standard MIMS and trap‐and‐release MIMS methods. The trap‐and‐release MIMS method gave the best signal to noise ratio spectra with detection limits down to 50 mg/L. Although the results presented are very preliminary, they suggest that rapid detection or even on‐line monitoring of this important group of biological metabolites might be possible with a MIMS system. Copyright © 1999 John Wiley & Sons, Ltd.