Premium
Characterization and monitoring reaction of polyurethane dendritic wedges and dendrimers using matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry
Author(s) -
Puapaiboon Uraiwan,
Taylor Richard T.
Publication year - 1999
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(19990330)13:6<508::aid-rcm516>3.0.co;2-q
Subject(s) - dendrimer , chemistry , mass spectrometry , matrix assisted laser desorption/ionization , reflectron , desorption , porphyrin , ionization , time of flight mass spectrometry , analytical chemistry (journal) , polyurethane , matrix (chemical analysis) , photochemistry , chromatography , polymer chemistry , organic chemistry , ion , adsorption
The purity of polyurethane dendritic wedges from first generation through fourth generation was verified by employing matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOFMS). First and third generation polyurethane porphyrin dendrimers, and tri‐core dendrimers obtained by attachment of the corresponding dendritic wedges to a porphyrin and to 1,3,5‐benzenetricarboxylic acid, were also mass analyzed by MALDI measurements. The spectra were acquired in both reflectron and linear mode. Due to the ease and speed of the analysis, MALDI‐TOF also proved to be a powerful tool in monitoring the progress of the reaction which can provide significant informative results that can be useful in designing and optimizing the synthesis. Copyright © 1999 John Wiley & Sons, Ltd.