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Characterization of supramolecular complexes by high resolution electrospray ionization mass spectrometry
Author(s) -
Hopfgartner Gérard,
Vilbois Francis,
Piguet Claude
Publication year - 1999
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(19990315)13:5<302::aid-rcm480>3.0.co;2-v
Subject(s) - chemistry , mass spectrometry , electrospray ionization , electrospray , resolution (logic) , analytical chemistry (journal) , ion trap , ion , ionization , characterization (materials science) , supramolecular chemistry , acetonitrile , chromatography , molecule , nanotechnology , organic chemistry , materials science , artificial intelligence , computer science
High resolution mass spectrometry on time‐of‐flight (TOF) and ion trap (IT) mass spectrometers is used for the qualitative speciation of a heterodimetallic triple‐stranded helicate [EuFe(L 1 ) 3 ](CIO 4 ) 5 and a toroidal complex [Ni 3 (L 2 ) 3 ](CIO 4 ) 6 (= circular single‐stranded helicate) dissolved in acetonitrile. The resolution of about 5000 at peak width at half height using ion trap mass spectrometry (ITMS) and time‐of‐flight mass spectrometry (TOFMS) combined with electrospray ionization (ESI) is sufficient to resolve sextuply charged ions leading to a straightforward characterization of the complexes in solution. The ESI‐MS response is influenced by the interface design, particularly for the heated capillary interface which requires optimized conditions for the study of non‐covalent complexes. Copyright © 1999 John Wiley & Sons, Ltd.