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Unexpected gas‐phase reactions of some underivatized disaccharides and of proton‐bound dimers of monosaccharides by liquid‐assisted secondary ion mass spectrometry
Author(s) -
Zapfe Svenja,
Müller Dietrich
Publication year - 1998
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(19980515)12:9<545::aid-rcm194>3.0.co;2-z
Subject(s) - chemistry , monosaccharide , mass spectrometry , disaccharide , ion , collision induced dissociation , mass spectrum , fast atom bombardment , glycosidic bond , chromatography , dissociation (chemistry) , isomerization , fragmentation (computing) , analytical chemistry (journal) , organic chemistry , tandem mass spectrometry , catalysis , operating system , computer science , enzyme
The positive liquid secondary ion mass spectrometry (LSIMS) spectra and LSIMS mass‐analyzed ion kinetic energy/collision activated dissociation (MIKE/CAD) spectra of three underivatized monosaccharides and fourteen disaccharides are discussed. Discrimination of the glycosidic linkage position and determination of the reducing end and the sequence of disaccharides are not possible, owing to the isomerization of bonds, in addition to the elimination of both sugar units as an anhydro sugar. Furthermore the fragmentations of [2M+H] + ions of monosaccharides, which appear to yield disaccharide ions on CAD, are discussed. © 1998 John Wiley & Sons, Ltd.