Premium
Matrix‐assisted laser desorption/ionization for short tandem repeat loci
Author(s) -
Taranenko N. I.,
Golovlev V. V.,
Allman S. L.,
Taranenko N. V.,
Chen C. H.,
Hong J.,
Chang L. Y.
Publication year - 1998
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(19980430)12:8<413::aid-rcm175>3.0.co;2-c
Subject(s) - chemistry , microsatellite , mass spectrometry , tandem , tandem mass spectrometry , ionization , desorption , matrix assisted laser desorption electrospray ionization , analytical chemistry (journal) , chromatography , matrix (chemical analysis) , laser , typing , matrix assisted laser desorption/ionization , genetics , ion , gene , biochemistry , optics , allele , materials science , physics , organic chemistry , adsorption , composite material , biology
Matrix‐assisted laser desorption/ionization was used for the detection of four base short tandem repeats (STR) for clinical samples using a time‐of‐flight mass spectrometer. Since STR plays an important role in genetic disease and human identification, this work indicates that laser desorption mass spectrometry has the potential to achieve rapid DNA typing for both forensic applications and genetic disease diagnosis. © 1998 John Wiley & Sons, Ltd.