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Characterization of stereoisomeric furanosidic derivatives by direct chemical ionization mass spectrometry and liquid secondary ion mass spectrometry with tandem mass spectrometry. (Part II)
Author(s) -
Borges C.,
Almoster Ferreira M. A.,
Van den Heuvel H.,
Claeys M.
Publication year - 1997
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(199707)11:11<1171::aid-rcm913>3.0.co;2-3
Subject(s) - chemistry , mass spectrometry , collision induced dissociation , tandem mass spectrometry , fragmentation (computing) , chemical ionization , direct electron ionization liquid chromatography–mass spectrometry interface , protein mass spectrometry , sample preparation in mass spectrometry , thermal ionization mass spectrometry , analytical chemistry (journal) , dissociation (chemistry) , top down proteomics , fast atom bombardment , electron ionization , ionization , ion , chromatography , electrospray ionization , organic chemistry , computer science , operating system
The present study deals with the mass spectrometric characterization of furanosidic compounds containing a 1,2‐O‐isopropylidene group using different mass spectrometric techniques: chemical ionization mass spectrometry and liquid secondary ion mass spectrometry together with metastable ion analysis and collision‐induced dissociation. Common fragmentation differences relate to the extent of the loss of water and the elimination of acetone. It is also shown that the introduction of a stable charge centre (Li + ) in the molecules is critical for observing a rearrangement involving hydrogen transfer in one of the two stereoisomeric pairs examined. © 1997 John Wiley & Sons, Ltd.