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Mass Spectrometry in the Study of Non‐enzymatic Glyco‐oxidation of Proteins
Author(s) -
Traldi Pietro,
Favretto Donata,
Seraglia Roberta,
Lapolla Annunziata
Publication year - 1997
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(199704)11:6<673::aid-rcm839>3.0.co;2-r
Subject(s) - chemistry , mass spectrometry , enzyme , in vivo , proteomics , chromatography , biochemistry , microbiology and biotechnology , gene , biology
Studies that have been performed by MALDI mass spectrometry in the field of non‐enzymatic protein glyco‐oxidation are briefly reviewed. The results obtained by in vitro and in vivo experiments demonstrate the power of this technique, which is able to give information on the number of sugar molecules condensed on specific proteins and, consequently, represents a new and specific diagnostic tool in diabetes control. © 1997 John Wiley & Sons, Ltd.