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Laser Ablation Ion Trap Mass Spectrometry—Storage Field Suppression and its Effect Upon Analytical Performance
Author(s) -
Gill C. G.,
Garrett A. W.,
Nogar N. S.,
Hemberger P. H.
Publication year - 1997
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(199704)11:6<551::aid-rcm914>3.0.co;2-f
Subject(s) - chemistry , mass spectrometry , ion trap , quadrupole ion trap , laser ablation , laser , ion trapping , ionization , ion , quadrupole , analytical chemistry (journal) , ion source , trap (plumbing) , atomic physics , chromatography , optics , physics , organic chemistry , meteorology
The combination of laser desorption and ablation with mass spectrometry has been, and will continue to be, a useful marriage of technologies. Quadrupole ion trap mass spectrometry, which has evolved from a simple mass selective detector for gas chromatography to a high performance analytical tool over the last decade, is being coupled more frequently with desorption sources, such as lasers and particle beams. The present work addresses a shortcoming of the use of laser sampling with quadrupole ion traps: laser ablation of samples directly within the storage volume of the trap can lead to suppression of the RF storage field, thereby reducing ion‐trapping efficiency during the ionization event. A systematic examination of the phenomenon has been conducted and the advantages of selective injection or ionization methods, such as resonant laser ablation, for elimination of this problem are presented. © 1997 John Wiley & Sons, Ltd.