Premium
Compact Tunable Cr:LiSAF Laser for Infrared Matrix‐assisted Laser Desorption/Ionization
Author(s) -
Sadeghi Mehrnoosh,
Olumee Zohra,
Tang Xiaodong,
Vertes Akos,
Jang ZhiXing,
Henderson Angus J.,
Lee Hyo Sang,
Prasad Coorg R.
Publication year - 1997
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(19970228)11:4<393::aid-rcm868>3.0.co;2-s
Subject(s) - chemistry , reproducibility , matrix assisted laser desorption electrospray ionization , laser , optical parametric oscillator , analytical chemistry (journal) , mass spectrometry , desorption , ionization , far infrared laser , infrared , matrix assisted laser desorption/ionization , matrix (chemical analysis) , optics , ion , chromatography , physics , adsorption , organic chemistry
A tunable Cr:LiSAF laser‐pumped optical parametric oscillator was used for mid‐infrared matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry experiments. The mass spectra of substance P, bovine insulin and pd(T) 10 in the 2.88–2.96 μm range showed excellent single shot signal quality (signal‐to‐noise ratio, resolution) but poor shot‐to‐shot reproducibility. The reproducibility is expected to improve with more stable laser design. No correlation was found between the absorption spectrum of the matrix and the MALDI response. © 1997 John Wiley & Sons, Ltd.