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Direct Coupling of Semi‐micro Liquid Chromatography and Sonic Spray Ionization Mass Spectrometry for Pesticide Analysis
Author(s) -
Hirabayashi Yukiko,
Takada Yasuaki,
Hirabayashi Atsumu,
Sakairi Minoru,
Koizumi Hideaki
Publication year - 1996
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(199612)10:15<1891::aid-rcm722>3.0.co;2-r
Subject(s) - chemistry , mass spectrometry , chromatography , direct electron ionization liquid chromatography–mass spectrometry interface , analytical chemistry (journal) , detection limit , ionization , chemical ionization , ambient ionization , sample preparation in mass spectrometry , simazine , atmospheric pressure chemical ionization , pesticide , electrospray ionization , ion , organic chemistry , agronomy , biology , atrazine
Direct coupling of semi‐micro liquid chromatography and sonic spray ionization mass spectrometry is demonstrated and shown to be a very powerful technique for pesticide analysis. Direct coupling is achieved by using a high flow rate of nitrogen gas in sonic spray ionization and a high operating temperature in the sampling orifice of the atmospheric ionization mass spectrometer. The detection limit for simazine is about 300 fmol based on quantitative analysis in the range between 1 pmol and 1 nmol. A mixture of three pesticides was successfully analyzed using semi‐micro liquid chromatography/mass spectrometry.