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Photofragmentation Studies of Biomolecular Ions of Amino Acids Using a Tandem Reflectron Time‐of‐flight Mass Spectrometer
Author(s) -
Jia W. J.,
Ledingham K. W. D.,
Scott C. T. J.,
Kosmidis C.,
Singhal R. P.
Publication year - 1996
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/(sici)1097-0231(199610)10:13<1597::aid-rcm678>3.0.co;2-2
Subject(s) - reflectron , chemistry , mass spectrometry , tandem , tandem mass spectrometry , ion , protein mass spectrometry , chromatography , analytical chemistry (journal) , time of flight mass spectrometry , organic chemistry , aerospace engineering , ionization , engineering
A tandem reflectron time‐of‐flight mass spectrometer developed in Glasgow University was used for the investigation of photofragmentation of the molecular ions of the amino acid derivatives: PTH‐tryptophan, PTH‐valine, and PTH‐alanine as well as of cytosine and guanine. The molecular ions were generated by matrix‐assisted laser desorption/ionization and the laser photofragmentation of selected ions took place at the turn‐around point of ions in the reflectron. The fragmentation mass spectra of the molecular ions of these amino acid derivatives have been observed and possible fragmentation pathways are discussed.