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Short Communication. Prenatal detection of a congenital pancreatic cyst and Beckwith–Wiedemann Syndrome
Author(s) -
Fremond B.,
Poulain P.,
Odent S.,
Milon J.,
Treguier C.,
Babut J. M.
Publication year - 1997
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/(sici)1097-0223(199703)17:3<276::aid-pd52>3.0.co;2-7
Subject(s) - beckwith–wiedemann syndrome , medicine , cyst , in utero , prenatal diagnosis , prenatal ultrasound , fetus , differential diagnosis , dysplasia , pancreatic disease , pathology , pancreas , pregnancy , biology , gene expression , genetics , gene , dna methylation , biochemistry
We report a case of congenital pancreatic cyst detected prenatally by ultrasound in a fetus with evidence for a diagnosis of Beckwith–Wiedemann syndrome (BWS). Neonatal hypoglycaemia was prevented. The cyst was managed by internal drainage. This is the second reported case of BWS associated with pancreatic cystic dysplasia and the first time that this association has been detected prenatally. Differential diagnosis of cystic abdominal lesions occurring in utero should take pancreatic cysts into consideration. This case suggests that pancreatic cysts should be included in the BWS phenotype. © 1997 by John Wiley & Sons, Ltd.