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PRENATAL DIAGNOSIS OF BLACKFAN–DIAMOND SYNDROME: CASE REPORT AND REVIEW OF THE LITERATURE
Author(s) -
MCLENNAN ANDREW C.,
CHITTY LYN S.,
RISSIK JUDY,
MAXWELL DARRYL J.
Publication year - 1996
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/(sici)1097-0223(199604)16:4<349::aid-pd854>3.0.co;2-#
Subject(s) - medicine , hydrops fetalis , diamond–blackfan anemia , in utero , prenatal diagnosis , pediatrics , fetus , obstetrics , pregnancy , ribosome , rna , biochemistry , genetics , chemistry , gene , biology
A case of prenatally diagnosed autosomal dominant congenital hypoplastic anaemia (Blackfan–Diamond syndrome or Aase congenital anaemia) causing hydrops fetalis is presented. Recommendations for the prenatal management of Blackfan–Diamond syndrome (BDS) include prepregnancy counselling for parents with BDS, detailed and serial fetal ultrasonography and echocardiography, cordocentesis if there are signs of anaemia, consideration of in utero transfusions and planned early delivery if the fetus is affected.