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MEASUREMENT OF AMNIOCHORIONIC MEMBRANE THICKNESS USING HIGH‐FREQUENCY ULTRASOUND
Author(s) -
FRIGO P.,
LANG CH.,
GOLASZEWSKI T.,
GRUBER D.,
BERGER A.,
ULRICH R.,
EPPEL W.,
HUBER J.
Publication year - 1996
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/(sici)1097-0223(199604)16:4<313::aid-pd849>3.0.co;2-0
Subject(s) - prom , ultrasound , high frequency ultrasound , medicine , linear regression , membrane , statistical analysis , nuclear medicine , radiology , obstetrics , chemistry , mathematics , statistics , biochemistry
Premature rupture of the membranes (PROM) accounts for approximately 30 per cent of all preterm deliveries. PROM is thought to be mainly due to a decrease in membrane integrity. The aim of our investigation was to determine, post‐partum after 28 normal deliveries, the thickness of the amniochorionic membrane using a 20 MHz high‐frequency ultrasound. The data obtained were compared with histological sections for measurement accuracy using a linear regression analysis method. The membrane thickness of the total study group was 0·83±0·11 mm (0·72–1·08 mm). Based on a statistical comparison with the histological sections, the high‐frequency ultrasound examination was shown to be highly reliable, with a correlation coefficient of r =0·96 ( P <0·0001). High‐frequency ultrasonographic examinations of membrane thickness are an objective and reliable method and may be a gain to prenatal diagnostics once this method can be used in vivo .