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A survey of seroprevalence of human papillomavirus types 16, 18 and 33 among children
Author(s) -
af Geijersstam Veronika,
Eklund Carina,
Wang Zhaohui,
Sapp Martin,
Schiller John T.,
Dillner Joakim,
Dillner Lena
Publication year - 1999
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/(sici)1097-0215(19990209)80:4<489::aid-ijc1>3.0.co;2-9
Subject(s) - seroprevalence , human papillomavirus , medicine , natural history , cervical cancer , hpv infection , epidemiology , virology , demography , immunology , antibody , cancer , serology , sociology
The importance and natural history of HPV infections in childhood is incompletely understood. We performed a survey for presence of serum antibodies to HPV capsids among 1031 children aged 0 to 13 years, resident in Stockholm, Sweden. The HPV seroprevalence among these children was 3.0% for HPV16, 0.6% for HPV18 and 2.7% for HPV33. By comparison, among simultaneously analyzed positive control panels comprising women with CIN or healthy women with type‐specific cervical HPV DNA, seroprevalence of HPV 16, 18 and 33 was 69%, 58% and 63% respectively. The results suggest that HPV infection in childhood is not common. Int. J. Cancer 80:489–493, 1999. © 1999 Wiley‐Liss, Inc.