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Growth inhibition of transplantable mouse tumors by non‐digestible carbohydrates
Author(s) -
Taper Henryk S.,
Delzenne Nathalie M.,
Roberfroid Marcel B.
Publication year - 1997
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/(sici)1097-0215(19970611)71:6<1109::aid-ijc30>3.0.co;2-5
Subject(s) - inulin , basal (medicine) , carbohydrate , biology , vernier scale , starch , pectin , endocrinology , medicine , biochemistry , chemistry , diabetes mellitus , cartography , geography
The possible influence of dietary non‐digestible carbohydrates (15% oligofructose, inulin or pectin incorporated in basal diet) on the growth of intramuscularily transplanted mouse tumors, from 2 tumor lines (TLT and EMT6), was investigated. The results were evaluated by regular tumor measurements with Vernier caliper. Mean tumor surface in experimental groups was compared with that in animals of control group fed basal diet containing starch as the only carbohydrate. The growth of both tumor lines was significantly inhibited by supplementation of non‐digestible carbohydrates. Int. J. Cancer 71: 1109‐1112, 1997. © 1997 Wiley‐Liss Inc.