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Genetic pre‐disposition to colorectal cancer: Initiation of a prospective study in Eastern Ontario
Author(s) -
Lagarde Alain E.,
Stern Hartley S.
Publication year - 1996
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/(sici)1097-0215(19960220)69:1<68::aid-ijc18>3.0.co;2-g
Subject(s) - colorectal cancer , disposition , oncology , medicine , prospective cohort study , cancer , psychology , social psychology
A pilot study which is part of both a larger provincial initiative and a network is in progress to address the question of genetic pre‐disposition to non‐polyposis colorectal cancer in eastern Ontario (population 1,200,000). It is modeled along a dual process of recruitment of at‐risk individuals based on either prior documentation of family histories or a close relationship to patients who are hospitalized for colorectal cancer treatment. The molecular diagnostic and genetic counseling components of the project are in their initial phase of operation while follow‐up strategies are being planned. © 1996 Wiley‐Liss, Inc.