Open AccessBrain activation in the processing of Chinese characters and words: A functional MRI study
Author(s) -
Tan Li Hai,
Spinks John A.,
Gao JiaHong,
Liu HoLing,
Perfetti Charles A.,
Xiong Jinhu,
Stofer Kathryn A.,
Pu Yonglin,
Liu Yijun,
Fox Peter T.
Publication year - 2000
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/(sici)1097-0193(200005)10:1<16::aid-hbm30>3.0.co;2-m
Subject(s) - laterality , psychology , lateralization of brain function , functional magnetic resonance imaging , chinese characters , dissociation (chemistry) , character (mathematics) , reading (process) , cognitive psychology , stimulus (psychology) , neuroscience , audiology , linguistics , computer science , artificial intelligence , medicine , chemistry , philosophy , geometry , mathematics
Functional magnetic resonance imaging was used to identify the neural correlates of Chinese character and word reading. The Chinese stimuli were presented visually, one at a time. Subjects covertly generated a word that was semantically related to each stimulus. Three sorts of Chinese items were used: single characters having precise meanings, single characters having vague meanings, and two‐character Chinese words. The results indicated that reading Chinese is characterized by extensive activity of the neural systems, with strong left lateralization of frontal (BAs 9 and 47) and temporal (BA 37) cortices and right lateralization of visual systems (BAs 17–19), parietal lobe (BA 3), and cerebellum. The location of peak activation in the left frontal regions coincided nearly completely both for vague‐ and precise‐meaning characters as well as for two‐character words, without dissociation in laterality patterns. In addition, left frontal activations were modulated by the ease of semantic retrieval. The present results constitute a challenge to the deeply ingrained belief that activations in reading single characters are right lateralized, whereas activations in reading two‐character words are left lateralized. Hum. Brain Mapping 10:16–27, 2000. © 2000 Wiley‐Liss, Inc.