Open AccessERP and fMRI measures of visual spatial selective attention
Author(s) -
Mangun George R.,
Buonocore Michael H.,
Girelli Massimo,
Jha Amishi P.
Publication year - 1998
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/(sici)1097-0193(1998)6:5/6<383::aid-hbm10>3.0.co;2-z
Subject(s) - psychology , extrastriate cortex , functional magnetic resonance imaging , neuroscience , electroencephalography , n2pc , cognitive psychology , visual cortex , p200 , audiology , visual perception , perception , medicine
In two prior studies, we investigated the neural mechanisms of spatial attention using a combined event‐related potential (ERP) and positron emission tomography (PET) approach (Heinze et al. [1994]: Nature 392:543–546; Mangun et al. [1997]: Hum Brain Mapp 5:273–279). Neural activations in extrastriate cortex were observed in the PET measures for attended stimuli, and these effects were related to attentional modulations in the ERPs at specific latencies. The present study used functional magnetic resonance imaging (fMRI) and ERPs in single subjects to investigate the intersubject variability in extrastriate spatial attention effects, and to qualitatively compare this to variations in ERP attention effects. Activations in single subjects replicated our prior group‐averaged PET findings, showing attention‐related increases in blood flow in the posterior fusiform and middle occipital gyri in the hemisphere contralateral to attended visual stimuli. All subjects showed attentional modulations of the occipital P1 component of the ERPs. These findings in single subjects demonstrate the consistency of extrastriate attention effects, and provide information about the feasibility of this approach for integration of electrical and functional imaging data. Hum. Brain Mapping 6:383–389, 1998. © 1998 Wiley‐Liss, Inc.