Open AccessTesting for anatomically specified regional effects
Author(s) -
Friston K.J.
Publication year - 1997
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/(sici)1097-0193(1997)5:2<133::aid-hbm7>3.0.co;2-4
Subject(s) - parametric statistics , statistical hypothesis testing , simple (philosophy) , statistical parametric mapping , computer science , statistical analysis , statistics , artificial intelligence , mathematics , magnetic resonance imaging , medicine , philosophy , epistemology , radiology
We present a simple method that allows statistical inferences to be made about the significance of regional effects in statistical parametric maps (SPMs) when the approximate location of the effect is specified in advance. The test can be thought of as analogous to assessing activations with uncorrected P values based on the height of SPMs but, in this instance, using the spatial extent or volume of the nearest activated region. The advantage of the current test is that it eschews a correction for multiple comparisons even though the exact location of the expected activation may not be known. Hum. Brain Mapping 5:133–136, 1997. © 1997 Wiley‐Liss, Inc.