Open AccessFunctional reorganization induced by endovascular embolization of a cerebral AVM
Author(s) -
Marshall Randolph S.,
HaceinBey Lotfi,
Young William L.,
PileSpellman John,
Das Sam,
Perera Gerard,
Mohr J. P.
Publication year - 1996
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/(sici)1097-0193(1996)4:3<168::aid-hbm2>3.0.co;2-1
Subject(s) - single photon emission computed tomography , cerebral blood flow , embolization , medicine , arteriovenous malformation , angiography , radiology , vasodilation , cerebral angiography , functional imaging , intracranial arteriovenous malformations , nuclear medicine , cardiology
We mapped motor function in a patient with a cerebral arteriovenous malformation (AVM) before and after treatment with endovascular embolization. Functional activation using technetium‐99m‐hexamethylpropyleneamine single photon emission tomography ( 99m Tc‐HMPAO‐SPECT) demonstrated a redistribution of regional cerebral blood flow (rCBF) that correlated with clinical improvement. Intravascular feeding artery pressure measurements, serial angiography, and challenge with a pharmacological vasodilator enabled us to explore possible mechanisms of functional reorganization. © 1996 Wiley‐Liss, Inc.