Open AccessComparison of primary motor cortex localization using functional magnetic resonance imaging and magnetoencephalography
Author(s) -
Sanders John A.,
Lewine Jeffrey D.,
Orrison William W.
Publication year - 1996
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/(sici)1097-0193(1996)4:1<47::aid-hbm3>3.0.co;2-p
Subject(s) - magnetoencephalography , functional magnetic resonance imaging , primary motor cortex , neuroscience , magnetic resonance imaging , motor cortex , psychology , functional imaging , nuclear magnetic resonance , medicine , physics , electroencephalography , radiology , stimulation
The primary goal of the study was to compare estimates of motor cortex localization from functional magnetic resonance imaging (FMRI) and magnetoencephalography (MEG). Thirteen normal volunteers were studied using both methods. FMRI was performed on a clinical 1.5 T system using gradient‐echo acquisitions and basic t ‐test processing. MEG primary motor field was characterized by a single dipole model. Comparisons between the location of the best‐fitting MEG dipole and the FMRI activation results were made using both fixed regions‐of‐interest weighted averaging and clustering analysis to reduce the observed FMRI activations to a single representative location. Both FMRI and MEG identified expected anatomic regions of primary motor activity and there was overall agreement to within 10 mm between these two functional imaging modalities. Given the observed agreement between these two techniques, it does not appear that the proposed artifactual mechanisms of local bulk motions or large‐vessel sensitivity will seriously preclude the clinical utility of FMRI for preoperative localization of sensorimotor cortex. © 1996 Wiley‐Liss, Inc.