Open AccessFunctions of motor proteins in echinoderm embryos: An argument in support of antibody inhibition experiments
Author(s) -
Scholey Jonathan M.
Publication year - 1998
Publication title -
cell motility and the cytoskeleton
Language(s) - English
Resource type - Journals
eISSN - 1097-0169
pISSN - 0886-1544
DOI - 10.1002/(sici)1097-0169(1998)39:4<257::aid-cm1>3.0.co;2-0
Subject(s) - biology , echinoderm , cytokinesis , microbiology and biotechnology , cytoskeleton , motor protein , microtubule , actin , motile cilium , morphogenesis , mitosis , myosin , cell , cilium , cell division , biochemistry , ecology , gene
Antibody inhibition experiments are proving to be extremely valuable in probing the in vivo functions of actin‐ and microtubule‐based motor proteins in the early development of echinoderm embryos, despite some skepticism among many cell biologists concerning the reliability of this approach. Antibody inhibition has revealed that motor proteins participate in diverse events during early echinoderm development, including mitosis, cytokinesis, the transport of exocytotic vesicles, and the assembly of motile cilia. Cell Motil. Cytoskeleton 39:257–260, 1998. © 1998 Wiley‐Liss, Inc.