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Caution concerning micrometastatic breast carcinoma in sentinel lymph nodes
Author(s) -
Allred D. Craig,
Elledge Richard M.
Publication year - 1999
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/(sici)1097-0142(19990915)86:6<905::aid-cncr1>3.0.co;2-k
Subject(s) - medicine , lymph , sentinel lymph node , micrometastasis , incidence (geometry) , breast carcinoma , axillary lymph nodes , breast cancer , immunohistochemistry , pathology , oncology , cancer , physics , optics
A pilot study by Dowlatshahi et al. observed a high (58%) incidence of micrometastases in the sentinel lymph nodes (SLNs) of patients with small primary breast carcinomas when immunohistochemical preparations of serial sections of the lymph nodes were examined. The prognostic implications of these findings are unknown and, until they are, evaluating SLNs in this manner should be avoided in routine clinical practice. See also pages 990–6.