Premium
Loss of heterozygosity analysis to diagnose adrenal cortical carcinoma
Author(s) -
Mansukhani Mahesh M.,
Greenebaum Ellen
Publication year - 1999
Publication title -
cancer cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/(sici)1097-0142(19990825)87:4<173::aid-cncr1>3.0.co;2-c
Subject(s) - loss of heterozygosity , medicine , adenoma , pathology , carcinoma , biology , biochemistry , allele , gene
The feasibility of performing loss of heterozygosity analysis on microdissected fine‐needle aspiration material from adrenal cortical lesions has been demonstrated. However, a larger number of cases and controls needs to be examined with this technique to determine its sensitivity, specificity, and clinical usefulness in distinguishing adrenal cortical carcinoma from adenoma. See also pages 176–7 and 231–7.