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When a human tumor xenograft is not a human tumor
Author(s) -
Krishan Awtar
Publication year - 1998
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/(sici)1097-0142(19981101)83:9<1889::aid-cncr2>3.0.co;2-s
Subject(s) - medicine , cancer research , pathology , oncology
Human tumors grown as xenografts in athymic nude mice are important tools for the study of tumor biology and experimental therapy. However, data presented by Pathak et al. indicate that a significant number of the xenografts they examined were not of human origin. Utilization of methods to confirm the human origin of xenografts in athymic mice is highly recommended. See also pages 1891‐3.