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Body mass predicts the survival of patients with new international federation of gynecology and obstetrics stage IB1 and IB2 cervical carcinoma treated with radical hysterectomy
Author(s) -
Finan Michael A.,
Hoffman Mitchel S.,
Chambers Richard,
Fiorica James V.,
DeCesare Stephen,
Kline Richard C.,
Roberts William S.,
Cavanagh Denis
Publication year - 1998
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/(sici)1097-0142(19980701)83:1<98::aid-cncr13>3.0.co;2-7
Subject(s) - medicine , body mass index , stage (stratigraphy) , radical hysterectomy , cervical cancer , lymph node , obstetrics and gynaecology , hysterectomy , carcinoma , obstetrics , gynecology , oncology , surgery , cancer , pregnancy , paleontology , genetics , biology
BACKGROUND The authors evaluated the impact of body mass on survival and morbidity of patients with new International Federation of Gynecology and Obstetrics (FIGO) Stage IB1 and IB2 cervical carcinoma managed with radical hysterectomy. METHODS Two hundred twenty‐nine patients with Stage IB1 or IB2 cervical carcinoma treated with radical hysterectomy were studied in a multivariate logistic regression analysis. The body mass index (BMI) and the ponderal index (PI) were used as measures of body mass and were analyzed as predictors of recurrence, survival, and complications in light of the new staging system. RESULTS Twenty‐seven of 229 patients died of recurrent disease. A low BMI or a high PI were predictive of poor survival. Tumor greatest dimension, lymph node involvement, BMI, and PI were all independent predictors of survival ( P = 0.0006). The only independent predictor of complications was para‐aortic lymph node dissection ( P = 0.0026). CONCLUSIONS Cervical carcinoma patients with a low body mass, as indicated by a low BMI or a high PI, were found to have poor survival after undergoing radical hysterectomy. Additional predictors of poor survival included lymph node metastases and increased tumor size. BMI and PI are more important predictors of survival than the new FIGO Stages IB1 and IB2. Body mass is not predictive of complications. Cancer 1998;83:98‐102. © 1998 American Cancer Society.