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The cytopathology of synovial sarcoma
Author(s) -
Ryan Mitchell R.,
Stastny Janet F.,
Wakely Paul E.
Publication year - 1998
Publication title -
cancer cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/(sici)1097-0142(19980225)84:1<42::aid-cncr7>3.0.co;2-h
Subject(s) - pathology , cytopathology , synovial sarcoma , medicine , histopathology , sarcoma , fibrosarcoma , h&e stain , cytology , anatomy , stroma , staining , immunohistochemistry
BACKGROUND In this article, the architectural and cytologic features of synovial sarcoma are described. METHODS Romanowsky‐ and Papanicolaou‐stained fine‐needle aspiration smears and corresponding hematoxylin and eosin sections were retrieved from archival material and examined by light microscopy. RESULTS Microtissue fragments comprised of spindle cells dominated smears and correlated with fibrosarcoma‐like areas prevalent in tissue sections. Characteristic fascicular and whorled patterns were apparent, and matrix material representing collagenous stroma varied from fibrillary to hyalinized. Epithelial components included polygonal and rectangular cells isolated from spindle cells, gland‐like formations occurring within otherwise spindle cell microtissue fragments, and clubbed, spindle cell collections lined by flattened epithelial cells. CONCLUSIONS Features of synovial sarcoma as defined previously by histopathology were apparent in cytologic preparations, facilitating a primary diagnosis by cytology. Cancer (Cancer Cytopathol) 1998;84:42‐9. © 1998 American Cancer Society.