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Gliomatosis cerebri: Results with radiation therapy
Author(s) -
Cozad Scott C.,
Townsend Patrick,
Morantz Robert A.,
Jenny Arthur B.,
Kepes John J.,
Smalley Stephen R.
Publication year - 1996
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/(sici)1097-0142(19961015)78:8<1789::aid-cncr20>3.0.co;2-t
Subject(s) - medicine , radiation therapy , quality of life (healthcare) , cancer , surgery , nursing
BACKGROUND This review was undertaken to determine the outcome for patients diagnosed in the modern era and treated with radiation therapy. METHODS Using the tumor registries of six institutions in a large metropolitan area, cases of gliomatosis were identified and retrospectively reviewed. RESULTS The clinical course for each patient was unique. Deterioration during treatment, brief stabilization, and reversal of the clinical signs and symptoms with stability and high quality of life at 16 months from diagnosis characterized Patients 1, 2, and 3, respectively. CONCLUSIONS Radiotherapy for gliomatosis appears to stabilize or improve neurologic function in some patients. Its impact on survival will await additional reports and longer follow‐up. Cancer 1996;78:1789‐93.