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Interaction potentials for protein folding
Author(s) -
Seno Flavio,
Maritan Amos,
Banavar Jayanth R.
Publication year - 1998
Publication title -
proteins: structure, function, and bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.699
H-Index - 191
eISSN - 1097-0134
pISSN - 0887-3585
DOI - 10.1002/(sici)1097-0134(19980215)30:3<244::aid-prot4>3.0.co;2-k
Subject(s) - simple (philosophy) , protein folding , biological system , folding (dsp implementation) , native state , computational biology , chemistry , computer science , statistical physics , biophysics , physics , biology , crystallography , biochemistry , engineering , philosophy , epistemology , electrical engineering
We outline a general strategy for determining the effective coarse‐grained interactions between the amino acids of a protein from the experimentally derived native‐state structures. The method is, in principle, free from any adjustable or empirically determined parameters, and it is tested on simple models and compared with other existing approaches. Proteins 30:244–248, 1998. © 1998 Wiley‐Liss, Inc.