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Criteria for evaluating protein structures derived from comparative modeling
Author(s) -
Venclovas Česlovas,
Zemla Adam,
Fidelis Krzysztof,
Moult John
Publication year - 1997
Publication title -
proteins: structure, function, and bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.699
H-Index - 191
eISSN - 1097-0134
pISSN - 0887-3585
DOI - 10.1002/(sici)1097-0134(1997)1+<7::aid-prot3>3.0.co;2-o
Subject(s) - protein structure prediction , casp , protein structure , computational biology , computer science , chemistry , biology , biochemistry
Following the first experiment for the Critical Assessment of methods for protein Structure Prediction (CASP1), numerical criteria were devised to analyze the performance of prediction methods. We report here the criteria for comparative modeling, and how effective they were in CASP2. These criteria are intended to evolve into a set of numerical measures that provide a comprehensive assessment of the quality of a structure produced by comparative modeling, and provide a means of investigating which modeling methods are most effective, so as to establish where future effort may be most productively applied. Proteins, Suppl. 1:7–13, 1997. © 1998 Wiley‐Liss, Inc.