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Non‐ionizable Polyacrylic Hydrogels Sensitive to pH for Biomedical Applications
Author(s) -
Vázquez Blanca,
Gurruchaga Mariló,
Goñi Isabel,
Román Julio San
Publication year - 1997
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/(sici)1097-0126(199706)43:2<182::aid-pi726>3.0.co;2-d
Subject(s) - self healing hydrogels , swelling , copolymer , polymer chemistry , reactivity (psychology) , radical polymerization , monomer , azobisisobutyronitrile , materials science , methacrylate , chemistry , composite material , polymer , medicine , alternative medicine , pathology
Hydrogels based on ethoxytriethyleneglycol monomethacrylate/methyl methacrylate (T/M) copolymers were prepared by free radical polymerization at 70°C in bulk with azobisisobutyronitrile as initiator. The reactivity ratios were calculated by Fineman–Ross (FR) and Kelen–Tudos (KT) linearization methods and by the non‐linear least square method suggested by Tidwell and Mortimer (TM). The reactivity ratios obtained were r T =0·17±0·03, r M =0·70±0·01 (FR method); r T =0·19±0·02, r M =0·76±0·03 (KT method) and r T =0·18; r M = 0·75 (TM method). Microstructure was obtained in terms of the distribution of T‐ and M‐centred triads. The swelling behaviour of the hydrogels was studied by immersion of the films in water and in buffered solutions at various pH values and it was analysed by comparison with that of poly(ethoxytriethyleneglycol monomethacrylate). It was observed that not only the average copolymer composition but also the distribution of monomeric sequences play an important role in the swelling behaviour. © 1997 SCI.