Premium
Synthesis and Evaluation of β‐Cyclodextrin–2‐Hydroxyethyl Methacrylate Copolymer as a Novel Adsorbent
Author(s) -
Sreenivasan K.
Publication year - 1997
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/(sici)1097-0126(199701)42:1<22::aid-pi643>3.0.co;2-k
Subject(s) - methacrylate , isocyanate , polymer , copolymer , adsorption , cyclodextrin , 2 hydroxyethyl methacrylate , polymer chemistry , materials science , chemistry , chromatography , organic chemistry , polyurethane
2‐Hydroxyethyl methacrylate (0·01mol) was allowed to react with 0·01mol of hexamethylene di‐isocyanate and the product was coupled to 0·01mol of β‐cyclodextrin to form a new cyclodextrin‐based copolymer. The interaction of the polymer with different steroids was investigated and the extent of adsorption was in the order cholesterol>progesterone>testosterone. The results indicate that the new polymer matrix could be used for the removal of steroids, particularly cholesterol, from a given medium. The polymer could also be used for sample purification, such as the removal of progesterone from a mixture prior to its analysis by other analytical techniques. The preliminary results show that the polymer may have interesting clinical and analytical applications. © of SCI.