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Outcome of pregnancies in women with uterine duplication anomalies
Author(s) -
Cooney Michael J.,
Benson Carol B.,
Doubilet Peter M.
Publication year - 1998
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/(sici)1097-0096(199801)26:1<3::aid-jcu2>3.0.co;2-l
Subject(s) - medicine , miscarriage , obstetrics , pregnancy , gestation , gestational age , exact test , gynecology , percentile , uterus , birth weight , apgar score , statistics , genetics , mathematics , biology
Purpose This study was conducted to compare pregnancy outcomes in women with uterine duplication anomalies with outcomes in women with normal uteri. Methods We studied 22 women with uterine duplication anomalies in whom first‐trimester sonography demonstrated a live fetus and compared pregnancy outcomes in these patients with outcomes in 66 women with normal‐appearing uteri (controls). The 2 groups were matched for gestational age at the time of first‐trimester sonography. Results Uterine duplication anomalies were associated with a higher miscarriage rate than were normal‐appearing uteri (23% versus 6%, p < 0.05, Fisher's exact test). Deliveries resulting in liveborn infants occurred earlier in women with anomalous uteri. The mean gestational age at delivery was 37.0 weeks for women with duplication anomalies versus 38.8 weeks for controls ( p < 0.05, Student's t ‐test), and a higher percentage of duplication anomaly patients delivered before 34 weeks' gestation (29% versus 3%, p < 0.01, Fisher's exact test). Neonates born from anomalous uteri had lower mean birth‐weight percentiles than did neonates in the control group (51st versus 68th percentile, p < 0.05, t ‐test). There was no difference in Apgar scores between the 2 groups at 1 and 5 minutes. Conclusions Women with duplication anomalies of the uterus have a higher miscarriage rate, deliver earlier, and have infants with lower birth‐weight percentiles than do women with normal‐appearing uteri. © 1998 John Wiley & Sons, Inc. J Clin Ultrasound 26 : 3–6, 1998.