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Thyroid autonomy with color‐coded image‐directed Doppler sonography: Internal hypervascularization for the recognition of autonomous adenomas
Author(s) -
Becker Dirk,
Bair HansJürgen,
Becker Wolfgang,
Günter Erwin,
Lohner Walter,
Lerch Stefan,
Hahn Eckart Georg
Publication year - 1997
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/(sici)1097-0096(199702)25:2<63::aid-jcu3>3.0.co;2-h
Subject(s) - medicine , thyroid nodules , color doppler , scintigraphy , thyroid , adenoma , radiology , predictive value , doppler sonography , differential diagnosis , ultrasound , prospective cohort study , nuclear medicine , ultrasonography , pathology
In a prospective study, we assessed the possibility of recognizing autonomous adenomas of the thyroid with color‐coded image‐directed Doppler sonography using internal hypervascularization in thyroid nodules for identification. Fifty‐three patients with thyroid nodules underwent additional CCDS examination and nuclear scintigraphy (reference). Of 29 patients having autonomous adenomas, 28 patients presented internal hypervascularization in their nodules resulting in a sensitivity of 96% and a specificity was 75%. Interestingly CCDS detected six adenomas in patients showing normal laboratory data (bTSH, TT 3 , FT 4 ). CCDS could be used to exclude focal adenomas with a negative predictive value of 94%. The positive predictive value for adenoma was 82%. © 1997 John Wiley & Sons, Inc.