Premium
Fetal breasts in normal and down syndrome fetuses
Author(s) -
Petrikovsky Boris M.,
Schneider Elizabeth P.,
Klein Victor R.,
Wyse Linda J.,
Lesser Martin
Publication year - 1996
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/(sici)1097-0096(199611/12)24:9<507::aid-jcu3>3.0.co;2-r
Subject(s) - medicine , fetus , trisomy , ultrasound , down syndrome , obstetrics , pregnancy , radiology , genetics , psychiatry , biology
To assess the validity of fetal breast size measurement as a sonographic marker in fetuses with Down syndrome. Methods: Fetal breasts were studied in 26 fetuses with trisomy 21 and 78 fetuses with normal chromosomes. Breasts were identified and measured in a cross‐sectional plane of the fetal chest at the level of the four‐chamber view of the heart. Normal fetuses had a mean breast size of 3.8 mm ± 1.1 mm. Fetuses with Down syndrome had a mean breast size of 1.9 mm ± 0.7 mm ( p ⩽ 0.0001). Diminished breast size measured by ultrasound in the second trimester may be helpful in identifying fetuses with Down syndrome. © 1996 John Wiley & Sons, Inc.