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Transvaginal sonography of the yolk sac in normal and abnormal pregnancy
Author(s) -
Stampone C.,
Nicotra M.,
Muttinelli C.,
Cosmi E. V.
Publication year - 1996
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/(sici)1097-0096(199601)24:1<3::aid-jcu1>3.0.co;2-n
Subject(s) - medicine , yolk sac , transvaginal sonography , pregnancy , gestation , obstetrics , predictive value , abortion , gynecology , first trimester , predictive value of tests , embryo , genetics , biology , microbiology and biotechnology
A cross‐sectional study comprising 117 consecutive first trimester singleton pregnancies was performed using transvaginal sonography (TVS) to evaluate size abnormalities of the secondary yolk sac (YS) vis‐à‐vis pregnancy outcome. In normal pregnancy outcome (NPO) the YS diameter showed an increase from the 5th to the 11th week, menstrual age, followed by a decrease and its disappearance after 12 weeks. A YS of abnormal size was statistically significant ( p < 0.001) in spontaneous abortion (SA) versus NPO, with a sensitivity of 68.7%, a specificity of 99%, a positive predictive value of 91.6% and a negative predictive value of 95.2%. These preliminary results indicate that a measurement of the YS very early in gestation may be a useful marker of pregnancy outcome. © 1996 John Wiley & Sons, Inc.