Premium
Single‐read sequence tags of a limited number of genomic DNA fragments provide an inexpensive tool for comparative genome analysis
Author(s) -
Hartung Kristina,
Frishman Dmitrij,
Hinnen Albert,
Wölfl Stefan
Publication year - 1998
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/(sici)1097-0061(1998100)14:14<1327::aid-yea321>3.0.co;2-l
Subject(s) - biology , synteny , genetics , genome , open reading frame , saccharomyces cerevisiae , genomic dna , dna , candida albicans , computational biology , sequence (biology) , comparative genomics , whole genome sequencing , dna sequencing , genomics , peptide sequence , gene
Single‐read sequences from both ends of 415 3‐kb average size genomic DNA fragments of Candida albicans were compared with the complete sequence data of Saccharomyces cerevisiae . Comparison at the protein level, translated DNA against protein sequences, revealed 138 sequence tags with clear similarity to S. cerevisiae proteins or open reading frames. One case of synteny was found for the open reading frames of RAD16 and LYS2 , which are adjacent to each other in S. cerevisiae and C. albicans . © 1998 John Wiley & Sons, Ltd.