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Sequence analysis of a 14·2 kb fragment of Saccharomyces cerevisiae chromosome XIV that includes the ypt53, tRNA Leu and gsr m2 genes and four new open reading frames
Author(s) -
GarciaCantalejo Jesus Manuel,
Boskovic Jasminka,
Jimenez Antonio
Publication year - 1996
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/(sici)1097-0061(199605)12:6<599::aid-yea938>3.0.co;2-9
Subject(s) - biology , cosmid , genetics , open reading frame , saccharomyces cerevisiae , accession number (library science) , gene , centromere , chromosome , peptide sequence , microbiology and biotechnology , genbank
As part of the EU yeast genome program, a fragment of 14 262 bp from the left arm of Saccharomyces cerevisiae chromosome XIV has been sequenced. This fragment corresponds to cosmid 14‐14b and is located roughly 130 kb from the centromere. It contains four new open reading frames which encode potential proteins of more than 99 amino acids, as well as the ypt53 , tRNA Leu and gsr m2 genes. The putative protein N2212 is similar to the ribosomal protein S7 from humans. N2215 contains several predicted transmembrane elements. N2231 contains regions which are rich in acidic, as well as basic, residues which could form α‐helical structures. Similar regions are found in a variety of proteins including glutamic acid rich protein, trichohyalin, caldesmon, Tb‐29 and several cytoskeleton‐interacting proteins. The sequence has been entered in the EMBL data library under Accession Number X85811.