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Molecular cloning of a third chitinase gene ( CHT1 ) from Candida albicans
Author(s) -
McCreath Kenneth J.,
Specht Charles A.,
Liu Yilun,
Robbins Phillips W.
Publication year - 1996
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/(sici)1097-0061(199604)12:5<501::aid-yea931>3.0.co;2-u
Subject(s) - biology , genbank , chitinase , candida albicans , nucleic acid sequence , gene , accession number (library science) , genetics , peptide sequence , cloning (programming) , sequence (biology) , molecular cloning , sequence alignment , microbiology and biotechnology , computer science , programming language
Here we report the complete nucleotide sequence of a third chitinase gene ( CHT1 ) from the dimorphic human pathogen Candida albicans . The deduced amino acid (aa) sequence of Cht1 consists of 416 aa and displays 36% protein sequence similarity to chitinases Cht2 and Cht3, from C. albicans . Interestingly the domain structure of Cht1 is truncated when compared to the other chitinases of C. albicans and lacks a Ser/Thr‐rich region. The sequence data will appear in the GenBank Nucleotide Sequence Data Library under the accession number U36490.