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Analysis of a 26 kb region on the left arm of yeast chromosome XV
Author(s) -
Mannhaupt Gertrud,
Vetter Irene,
Schwarzlose Christa,
Mitzel Sabine,
Feldmann Horst
Publication year - 1996
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/(sici)1097-0061(199601)12:1<67::aid-yea884>3.0.co;2-f
Subject(s) - biology , genetics , gene , intergenic region , accession number (library science) , coding region , nucleic acid sequence , chromosome , sequence (biology) , genbank , sequence analysis , open reading frame , dna sequencing , computational biology , peptide sequence , genome
In the framework of the EC programme for sequencing yeast chromosome XV, we have determined the nucleotide sequence of a 26 kb region. Subsequent analysis revealed 13 non‐overlapping open reading frames, three of which correspond to known yeast genes. A pair of tRNA genes associated with remnant Ty elements were localized in this region. From structural parameters and/or similarity searches with entries in the current data libraries, a preliminary functional assessment of several of the putative novel gene products can be made. The gene density in this region amounts to one gene in 2 kb. Protein coding regions occupy 61% of the total DNA sequence. Within the intergenic regions, potential regulatory elements can be predicted. The data obtained here may serve as a basis for a more detailed biochemical analysis of the novel genes. The complete nucleotide sequence of the 26 kb segment as depicted in Figure 1 has been deposited at the EBI data library under Accession Number X91067.